Gene code : from molecular basis toward cancer immunotherapy

The programmed death 1 receptor (PD-1) and its ligand (PD-L1) are key molecules of immune checkpoint mechanisms in cancer and actually represent one of the main targets of immunotherapy. The predictive and prognostic values of PD-L1 expression alone in cancer patients is currently under debate due t...

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Bibliographic Details
Main Authors: Federico Pio Fabrizio, Domenico Trombetta, Antonio Rossi, Angelo Sparaneo, Stefano Castellana, Lucia Anna Muscarella
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835918815598