Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology

Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology

The impact of natural killer (NK) cell alloreactivity on hematopoietic stem cell transplantation (HSCT) outcome is still debated due to the complexity of graft parameters, HLA class I environment, the nature of killer cell immunoglobulin-like receptor (KIR)/KIR ligand genetic combinations studied, a...

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Bibliographic Details
Main Authors: Bercelin Maniangou, Nolwenn Legrand, Mehdi Alizadeh, Ulysse Guyet, Catherine Willem, Gaëlle David, Eric Charpentier, Alexandre Walencik, Christelle Retière, Katia Gagne
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
high-resolution killer cell immunoglobulin-like receptor typing
allele polymorphism
next-generation sequencing
International Histocompatibility Workshop DNA samples
Natural killer cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00547/full

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.00547/full

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