Prion Protein Overexpression in Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Effectively Protected Rodent Kidney Against Ischemia-Reperfusion Injury Via Enhancing ATP/Mitochondrial Biogenesis—Role of ADMSC Rejuvenation and Proliferation

Prion Protein Overexpression in Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Effectively Protected Rodent Kidney Against Ischemia-Reperfusion Injury Via Enhancing ATP/Mitochondrial Biogenesis—Role of ADMSC Rejuvenation and Proliferation

Background: We tested the hypothesis that overexpression of cellular-prion-protein in adipose-derived mesenchymal stem cells (PrPC OE -ADMSCs) effectively protected the kidney against ischemia-reperfusion (IR) injury in rat. Methods: Part I of cell culture was categorized into A1(ADMSCs)/A2(ADMSCs+p...

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Bibliographic Details
Main Authors: Yen-Ta Chen, Chih-Chao Yang, John Y. Chiang, Pei-Hsun Sung, Pei-Lin Shao, Chi-Ruei Huang, Mel S. Lee, Hon-Kan Yip
Format: Article
Language:English
Published: SAGE Publishing 2023-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897231211067

Internet

https://doi.org/10.1177/09636897231211067

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