Downregulation of T-cell cytotoxic marker IL18R1 promotes cancer proliferation and migration and is associated with dismal prognosis and immunity in lung squamous cell carcinoma

Downregulation of T-cell cytotoxic marker IL18R1 promotes cancer proliferation and migration and is associated with dismal prognosis and immunity in lung squamous cell carcinoma

Immunotherapy can improve the survival of patients with advanced lung squamous cell carcinoma (LUSC). T cytotoxic cells are one of the main members of the immune microenvironment. Herein, we aimed to identify the roles of T-cell cytotoxic markers interleukin 18 (IL18) receptor 1 (IL18R1) in the LUSC...

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Bibliographic Details
Main Authors: Qiang Guo, Chuang-Yan Wu, Ni Jiang, Song Tong, Jun-Hao Wan, Xiao-Yue Xiao, Pei-Yuan Mei, Hua-Song Liu, Si-Hua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
interleukin 18 receptor 1
lung squamous cell carcinoma
immune microenvironment
T cytotoxic cells
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.986447/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.986447/full

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