Premature Discontinuation of Prospective Clinical Studies Approved by a Research Ethics Committee - A Comparison of Randomised and Non-Randomised Studies.

Premature Discontinuation of Prospective Clinical Studies Approved by a Research Ethics Committee - A Comparison of Randomised and Non-Randomised Studies.

Premature discontinuation of clinical studies affects about 25% of randomised controlled trials (RCTs) which raises concerns about waste of scarce resources for research. The risk of discontinuation of non-randomised prospective studies (NPSs) is yet unclear.To compare the proportion of discontinued...

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Bibliographic Details
Main Authors: Anette Blümle, Stefan Schandelmaier, Patrick Oeller, Benjamin Kasenda, Matthias Briel, Erik von Elm, DISCO study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5085068?pdf=render

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http://europepmc.org/articles/PMC5085068?pdf=render

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