Single-Cell and Bulk RNA Sequencing Reveal Malignant Epithelial Cell Heterogeneity and Prognosis Signatures in Gastric Carcinoma

Single-Cell and Bulk RNA Sequencing Reveal Malignant Epithelial Cell Heterogeneity and Prognosis Signatures in Gastric Carcinoma

Gastric carcinoma (GC) heterogeneity represents a major barrier to accurate diagnosis and treatment. Here, we established a comprehensive single-cell transcriptional atlas to identify the cellular heterogeneity in malignant epithelial cells of GC using single-cell RNA sequencing (scRNA-seq). A total...

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Bibliographic Details
Main Authors: Zhihong Huang, Chao Wu, Xinkui Liu, Shan Lu, Leiming You, Fengying Guo, Antony Stalin, Jingyuan Zhang, Fanqin Zhang, Zhishan Wu, Yingying Tan, Xiaotian Fan, Jiaqi Huang, Yiyan Zhai, Rui Shi, Meilin Chen, Chunfang Wu, Huiying Li, Jiarui Wu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
single-cell RNA sequencing
bulk RNA sequencing
gastric carcinoma
malignant epithelial cells
prognostic signatures
Online Access:https://www.mdpi.com/2073-4409/11/16/2550

Internet

https://www.mdpi.com/2073-4409/11/16/2550

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