Engineered Fragments of the PSMA-Specific 5D3 Antibody and Their Functional Characterization

Engineered Fragments of the PSMA-Specific 5D3 Antibody and Their Functional Characterization

Prostate-Specific Membrane Antigen (PSMA) is an established biomarker for the imaging and experimental therapy of prostate cancer (PCa), as it is strongly upregulated in high-grade primary, androgen-independent, and metastatic lesions. Here, we report on the development and functional characterizati...

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Bibliographic Details
Main Authors: Zora Novakova, Nikola Belousova, Catherine A. Foss, Barbora Havlinova, Marketa Gresova, Gargi Das, Ala Lisok, Adam Prada, Marketa Barinkova, Martin Hubalek, Martin G. Pomper, Cyril Barinka
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
prostate-specific membrane antigen
in vivo imaging
prostate cancer
monoclonal antibody
antibody fragment
glutamate carboxypeptidase II
Online Access:https://www.mdpi.com/1422-0067/21/18/6672

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https://www.mdpi.com/1422-0067/21/18/6672

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