The influence of intervertebral disc overloading on nociceptor calcium flickering

The influence of intervertebral disc overloading on nociceptor calcium flickering

Abstract Introduction Mechanical overloading can trigger a degenerative‐like cascade in an organ culture of intervertebral disc (IVD). Whether the overloaded IVD can influence the activation of nociceptors (i.e., the damage sensing neurons) remains unknown. The study aims to investigate the influenc...

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Bibliographic Details
Main Authors: Jan Gewiess, Janick Eglauf, Astrid Soubrier, Sibylle Grad, Mauro Alini, Marianna Peroglio, Junxuan Ma
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:JOR Spine
Subjects:
calcium imaging
dorsal root ganglion
intervertebral disc
organ culture
Online Access:https://doi.org/10.1002/jsp2.1267

Internet

https://doi.org/10.1002/jsp2.1267

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