Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance

Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance

Abstract Hypoxia-induced cisplatin resistance is a major challenge during non-small cell lung cancer (NSCLC) treatment. Based on previous studies, we further explored the effect of eukaryotic initiation factor 5A2 (eIF5A2) in hypoxia-induced cisplatin resistance. In this study, we found that autopha...

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Bibliographic Details
Main Authors: Guodong Xu, Hang Chen, Shibo Wu, Jiabin Chen, Shufen Zhang, Guofeng Shao, Lebo Sun, Yinyu Mu, Kaitai Liu, Qiaoling Pan, Ni Li, Xiaoxia An, Shuang Lin, Wei Chen
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05033-y

Internet

https://doi.org/10.1038/s41419-022-05033-y

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