Mechanism of action of disulfiram and research advances in anti-glomerular basement membrane type glomerulonephritis

Disulfiram is widely applied for treating chronic alcoholism. In recent years, researchers have proposed specific anti-cancer mechanisms by disulfiram, such as arresting the activity of acetaldehyde dehydrogenase (ALDH) and boosting intracellular reactive oxygen species (ROS)(reactive oxygen species...

Full description

Bibliographic Details
Main Authors: Yan-yu Zhang, Xin Lyu, Xiao-guang Huang, Xiao-jun Ren, Xue Wang, Wei-min Yu
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2024-03-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/cn/article/doi/10.3969/j.issn.1671-2390.2024.03.011