Comprehensive Analysis of MEN1 Mutations and Their Role in Cancer

MENIN is a scaffold protein encoded by the MEN1 gene that functions in multiple biological processes, including cell proliferation, migration, gene expression, and DNA damage repair. MEN1 is a tumor suppressor gene, and mutations that disrupts MEN1 function are common to many tumor types. Mutations...

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Bibliographic Details
Main Authors: Devi D. Nelakurti, Amrit L. Pappula, Swetha Rajasekaran, Wayne O. Miles, Ruben C. Petreaca
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/9/2616