Temporal transcriptomic analysis using TrendCatcher identifies early and persistent neutrophil activation in severe COVID-19

Studying temporal gene expression shifts during disease progression provides important insights into the biological mechanisms that distinguish adaptive and maladaptive responses. Existing tools for the analysis of time course transcriptomic data are not designed to optimally identify distinct tempo...

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Bibliographic Details
Main Authors: Xinge Wang, Mark A. Sanborn, Yang Dai, Jalees Rehman
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-04-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.157255