The Importance of Physiologically Relevant Cell Lines for Studying Virus–Host Interactions

Viruses interact intimately with the host cell at nearly every stage of replication, and the cell model that is chosen to study virus infection is critically important. Although primary cells reflect the phenotype of healthy cells in vivo better than cell lines, their limited lifespan makes experime...

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Bibliographic Details
Main Authors: David Hare, Susan Collins, Breanne Cuddington, Karen Mossman
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/8/11/297