Outer Membrane Vesicle Vaccines from Biosafe Surrogates Prevent Acute Lethal Glanders in Mice

Burkholderia mallei is a host-adapted Gram-negative mammalian pathogen that causes the severe disease glanders. Glanders can manifest as a rapid acute progression or a chronic debilitating syndrome primarily affecting solipeds and humans in close association with infected animals. In USA, B. mallei...

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Bibliographic Details
Main Authors: Michael H. Norris, Mohammad S. R. Khan, Sunisa Chirakul, Herbert P. Schweizer, Apichai Tuanyok
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/6/1/5