Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma

Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma

Cryoablation (CRA) and microwave ablation (MWA) are two main local treatments for hepatocellular carcinoma (HCC). However, which one is more curative and suitable for combining with immunotherapy is still controversial. Herein, CRA induced higher tumoral PD-L1 expression and more T cells infiltratio...

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Bibliographic Details
Main Authors: Jizhou Tan, Ting Liu, Wenzhe Fan, Jialiang Wei, Bowen Zhu, Yafang Liu, Lingwei Liu, Xiaokai Zhang, Songling Chen, Haibiao Lin, Yuanqing Zhang, Jiaping Li
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Hepatocellular carcinoma
Immunotherapy
Cryoablation
Microwave ablation
CXCL9
NK cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522003410

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http://www.sciencedirect.com/science/article/pii/S2211383522003410

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