Radiosynthesis, quality control, biodistribution, and infection-imaging study of a new 99mTc-labeled ertapenem radiopharmaceutical

Radiosynthesis, quality control, biodistribution, and infection-imaging study of a new 99mTc-labeled ertapenem radiopharmaceutical

Ertapenem is a member of carbapenem antibiotics used for the treatment of moderate-to-severe intra-abdominal, urinary tract, acute pelvic, and post-surgical gynecologic infections. The antibacterial activity of ertapenem is mediated through binding to penicillin-binding proteins which results in inh...

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Bibliographic Details
Main Authors: Syed Ali Raza Naqvi, Tania Jabbar, Maha A. Alharbi, Asma Noureen, Nada K. Alharbi, Tauqir A. Sherazi, Anum Shahzadi, Ahmed Ezzat Ahmed, M. Shahzad Afzal, M. Babar Imran
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Chemistry
Subjects:
nuclear medicine
metal complex
infection imaging
radiopharmaceuticals
SPECT imaging
ertapenem
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1020387/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.1020387/full

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