Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.

Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.

The Second Heart Field (SHF) has been implicated in several forms of congenital heart disease (CHD), including atrioventricular septal defects (AVSDs). Identifying the SHF gene regulatory networks required for atrioventricular septation is therefore an essential goal for understanding the molecular...

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Bibliographic Details
Main Authors: Andrew D Hoffmann, Xinan Holly Yang, Ozanna Burnicka-Turek, Joshua D Bosman, Xiaomeng Ren, Jeffrey D Steimle, Steven A Vokes, Andrew P McMahon, Vladimir V Kalinichenko, Ivan P Moskowitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4214600?pdf=render

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http://europepmc.org/articles/PMC4214600?pdf=render

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