Anti-CD19 chimeric antigen receptor T-cell followed by interferon−α therapy induces durable complete remission in donor cell-derived acute lymphoblastic leukemia: A case report

Anti-CD19 chimeric antigen receptor T-cell followed by interferon−α therapy induces durable complete remission in donor cell-derived acute lymphoblastic leukemia: A case report

Donor cell-derived leukemia (DCL) is a special type of relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Patients with DCL generally have a poor prognosis due to resistance to conventional chemotherapy. Here, we report a case of donor cell-derived acute lymphoblastic leuk...

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Bibliographic Details
Main Authors: Jing Ni, Junjie Zhou, Zhangbiao Long, Xin Chen, Xiaowen Chen, Jian Hong, Xinglin Liang, Qingsheng Li, Ruixiang Xia, Jian Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
chimeric antigen receptor T cell
interferon-α
durable complete remission
donor cell-derived leukemia
post-transplant recurrence
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1021786/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1021786/full

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