Reduced serum levels of anti-Mullerian hormone is a putative biomarker of early knee osteoarthritis in middle-aged females at menopausal transition

Abstract A recent epidemiological study revealed that the highest prevalence of early knee osteoarthritis (OA) was observed in females aged ≥ 50 years. The major causal factor of early knee OA was sex. Despite the relevance of estrogen in evaluating chondral and bone metabolism in OA, it is not easi...

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Bibliographic Details
Main Authors: Eiji Sasaki, Daisuke Chiba, Seiya Ota, Yuka Kimura, Shizuka Sasaki, Yuji Yamamoto, Maika Oishi, Kaori Iino, Masataka Ando, Eiichi Tsuda, Yasuyuki Ishibashi
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84584-0