Are FGFR and IDH1-2 alterations a positive prognostic factor in intrahepatic cholangiocarcinoma? An unresolved issue

Are FGFR and IDH1-2 alterations a positive prognostic factor in intrahepatic cholangiocarcinoma? An unresolved issue

Despite representing some of the most common and investigated molecular changes in intrahepatic cholangiocarcinoma (iCCA), the prognostic role of FGFR and IDH1/2 alterations still remains an open question. In this review we provide a critical analysis of available literature data regarding this topi...

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Bibliographic Details
Main Authors: Giovanni Brandi, Chiara Deiana, Linda Galvani, Andrea Palloni, Angela Dalia Ricci, Alessandro Rizzo, Simona Tavolari
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Oncology
Subjects:
FGFR
IDH
cholangiocarcinoma
prognosis
molecular alteration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1137510/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1137510/full

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