Structural basis of the membrane intramolecular transacylase reaction responsible for lyso-form lipoprotein synthesis
In Gram-positive bacteria, lipoprotein intramolecular transacylase Lit produces a lipoprotein variant with less immunogenicity. As such, Lit can be viewed as a virulence factor. Here, structural and functional characterization of the enzyme provides insight into its catalytic mechanism, setting the...
| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Nature Portfolio
2021-07-01
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| Reeks: | Nature Communications |
| Online toegang: | https://doi.org/10.1038/s41467-021-24475-0 |