PRMT5 Cooperates with pICln to Function as a Master Epigenetic Activator of DNA Double-Strand Break Repair Genes

PRMT5 Cooperates with pICln to Function as a Master Epigenetic Activator of DNA Double-Strand Break Repair Genes

Summary: DNA double-strand break (DSB) repair is critical for cell survival and genome integrity. Upon recognition of DSBs, repair proteins are transiently upregulated to facilitate repair through homologous recombination (HR) or non-homologous end joining (NHEJ). We present evidence that PRMT5 coop...

Full description

Bibliographic Details
Main Authors: Jake L. Owens, Elena Beketova, Sheng Liu, Samantha L. Tinsley, Andrew M. Asberry, Xuehong Deng, Jiaoti Huang, Chenglong Li, Jun Wan, Chang-Deng Hu
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900421930495X

Internet

http://www.sciencedirect.com/science/article/pii/S258900421930495X

Similar Items