Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis

Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis

Background: High-molecular-weight kininogen is a cofactor of the human contact system, an inflammatory response mechanism that is activated during sepsis. It has been shown that high-molecular-weight kininogen contributes to endotoxemia, but is not critical for local host defense during pneumonia by...

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Bibliographic Details
Main Authors: Juliane Köhler, Claudia Maletzki, Dirk Koczan, Marcus Frank, Armin Springer, Carolin Steffen, Alexey S. Revenko, A.Robert MacLeod, Stefan Mikkat, Bernd Kreikemeyer, Sonja Oehmcke-Hecht
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:EBioMedicine
Subjects:
Kininogen
Sepsis
Streptococcus pyogenes
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302838

Internet

http://www.sciencedirect.com/science/article/pii/S2352396420302838

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