SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis

SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis

Intestinal epithelial cells (IECs) constitute a defensive physical barrier in mucosal tissues and their disruption is involved in the etiopathogenesis of several inflammatory pathologies, such as Ulcerative Colitis (UC). Recently, the succinate receptor SUCNR1 was associated with the activation of i...

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Bibliographic Details
Main Authors: Cristina Bauset, Lluis Lis-Lopez, Sandra Coll, Laura Gisbert-Ferrándiz, Dulce C. Macias-Ceja, Marta Seco-Cervera, Francisco Navarro, Juan V. Esplugues, Sara Calatayud, Dolores Ortiz-Masia, Maria D. Barrachina, Jesús Cosín-Roger
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
Ulcerative Colitis
SUCNR1
epithelial cells
Online Access:https://www.mdpi.com/2227-9059/10/3/532

Internet

https://www.mdpi.com/2227-9059/10/3/532

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