Empagliflozin attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial homeostasis

Empagliflozin attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial homeostasis

Abstract Background Empagliflozin has been reported to protect endothelial cell function, regardless of diabetes status. However, the role of empagliflozin in microvascular protection during myocardial ischemia reperfusion injury (I/R) has not been fully understood. Methods Electron microscopy, west...

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Bibliographic Details
Main Authors: Rongjun Zou, Wanting Shi, Junxiong Qiu, Na Zhou, Na Du, Hao Zhou, Xinxin Chen, Li Ma
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cardiovascular Diabetology
Subjects:
Empagliflozin
Microvascular injury
Endothelial dysfunction
ischemia/reperfusion injury
Mitochondria
Online Access:https://doi.org/10.1186/s12933-022-01532-6

Internet

https://doi.org/10.1186/s12933-022-01532-6

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