Improvement of the Antioxidant and Antitumor Activities of Benzimidazole-Chitosan Quaternary Ammonium Salt on Drug Delivery Nanogels

Improvement of the Antioxidant and Antitumor Activities of Benzimidazole-Chitosan Quaternary Ammonium Salt on Drug Delivery Nanogels

The present study focused on the design and preparation of acid-responsive benzimidazole-chitosan quaternary ammonium salt (BIMIXHAC) nanogels for a controlled, slow-release of Doxorubicin HCl (DOX.HCl). The BIMIXHAC was crosslinked with sodium tripolyphosphate (TPP) using the ion crosslinking metho...

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Bibliographic Details
Main Authors: Bing Ma, Qing Li, Jingjing Zhang, Yingqi Mi, Wenqiang Tan, Zhanyong Guo
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Marine Drugs
Subjects:
benzimidazole-chitosan quaternary ammonium salt
acidic-responsive nanogels
antioxidant activity
antitumor activity
Online Access:https://www.mdpi.com/1660-3397/22/1/40

Internet

https://www.mdpi.com/1660-3397/22/1/40

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