NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance

NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance

Oral cancer is a major public health burden worldwide. The lack of biomarkers for early diagnosis has increased the difficulty in managing this disease. Recent studies have reported that neutrophil gelatinase-associated lipocalin (NGAL), a secreted glycoprotein, is upregulated in various tumors. In...

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Bibliographic Details
Main Authors: Javadi Monisha, Nand Kishor Roy, Ganesan Padmavathi, Kishore Banik, Devivasha Bordoloi, Amrita Devi Khwairakpam, Frank Arfuso, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Gautam Sethi, Alan Prem Kumar, Ajaikumar B. Kunnumakkara
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Cancers
Subjects:
oral cancer
mTOR pathway
secreted glycoprotein
drug resistance
Online Access:http://www.mdpi.com/2072-6694/10/7/228

Internet

http://www.mdpi.com/2072-6694/10/7/228

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