Real-world comprehensive genomic and immune profiling reveals distinct age- and sex-based genomic and immune landscapes in tumors of patients with non-small cell lung cancer

Real-world comprehensive genomic and immune profiling reveals distinct age- and sex-based genomic and immune landscapes in tumors of patients with non-small cell lung cancer

IntroductionYounger patients with non-small cell lung cancer (NSCLC) (<50 years) represent a significant patient population with distinct clinicopathological features and enriched targetable genomic alterations compared to older patients. However, previous studies of younger NSCLC suffer from...

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Bibliographic Details
Main Authors: Zachary D. Wallen, Heidi Ko, Mary K. Nesline, Stephanie B. Hastings, Kyle C. Strickland, Rebecca A. Previs, Shengle Zhang, Sarabjot Pabla, Jeffrey Conroy, Jennifer B. Jackson, Kamal S. Saini, Taylor J. Jensen, Marcia Eisenberg, Brian Caveney, Pratheesh Sathyan, Eric A. Severson, Shakti H. Ramkissoon
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Immunology
Subjects:
cancer
NSCLC
non-small cell lung cancer
tumor microenvironment
inflammation
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1413956/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1413956/full

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