Comprehensive analyses for the coagulation and macrophage-related genes to reveal their joint roles in the prognosis and immunotherapy of lung adenocarcinoma patients

Comprehensive analyses for the coagulation and macrophage-related genes to reveal their joint roles in the prognosis and immunotherapy of lung adenocarcinoma patients

PurposeThis study aims to explore novel biomarkers related to the coagulation process and tumor-associated macrophage (TAM) infiltration in lung adenocarcinoma (LUAD).MethodsThe macrophage M2-related genes were obtained by Weighted Gene Co-expression Network Analysis (WGCNA) in bulk RNA-seq data, wh...

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Bibliographic Details
Main Authors: Zhuoqi Li, Zongxiu Yin, Zupeng Luan, Chi Zhang, Yuanyuan Wang, Kai Zhang, Feng Chen, Zhensong Yang, Yuan Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
lung adenocarcinoma
coagulation
tumor-associated macrophage
risk score model
prognosis
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273422/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273422/full

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