AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery

AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery

Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity. However, a significant impediment to the broad clinical success of AAV-based therapies is the widespread pre...

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Bibliographic Details
Main Authors: Darrick L. Yu, Laura P. van Lieshout, Brenna A. Y. Stevens, Kelsie J. (Jagt) Near, Jenny K. Stodola, Kevin J. Stinson, Durda Slavic, Sarah K. Wootton
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Viruses
Subjects:
adeno-associated virus (AAV)
novel serotype
porcine capsid
bovine capsid
luciferase imaging
transduction
Online Access:https://www.mdpi.com/1999-4915/16/1/57

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https://www.mdpi.com/1999-4915/16/1/57

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