Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice

<p>Abstract</p> <p>Background</p> <p>Inheritance of the three different alleles of the human apolipoprotein (apo) E gene (<it>APOE</it>) are associated with varying risk or clinical outcome from a variety of neurologic diseases. ApoE isoform-specific modulat...

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Bibliographic Details
Main Authors: Montine Thomas J, Maeda Nobuyo, Maezawa Izumi, Montine Kathleen S
Format: Article
Language:English
Published: BMC 2006-04-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/3/1/10