Canonical and non-canonical JAK/STAT transcriptional targets may be involved in distinct and overlapping cellular processes

Abstract Background The Janus kinase-signal transducer and activator of transcription (JAK/STAT) pathway has been well-characterized as a crucial signal transduction cascade that regulates vital biological responses including development, immunity and oncogenesis. Additionally to its canonical pathw...

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Bibliographic Details
Main Authors: Amy Tsurumi, Connie Zhao, Willis X. Li
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-4058-y