Expression of Androgen Receptor Is Negatively Regulated By p53

Expression of Androgen Receptor Is Negatively Regulated By p53

Increased expression of androgen receptor (AR) in prostate cancer (PC) is associated with transition to androgen independence. Because the progression of PC to advanced stages is often associated with the loss of p53 function, we tested whether the p53 could regulate the expression of AR gene. Here...

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Bibliographic Details
Main Authors: Fatouma Alimirah, Ravichandran Panchanathan, Jianming Chen, Xiang Zhang, Shuk-Mei Ho, Divaker Choubey
Format: Article
Language:English
Published: Elsevier 2007-12-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Prostate cancer
androgen receptor
p53
DNA damage
transcriptional repression
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607801254

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http://www.sciencedirect.com/science/article/pii/S1476558607801254

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