The archaeal KEOPS complex possesses a functional Gon7 homolog and has an essential function independent of the cellular t6A modification level

The archaeal KEOPS complex possesses a functional Gon7 homolog and has an essential function independent of the cellular t6A modification level

Abstract Kinase, putative Endopeptidase, and Other Proteins of Small size (KEOPS) is a multisubunit protein complex conserved in eukaryotes and archaea. It is composed of Pcc1, Kae1, Bud32, Cgi121, and Gon7 in eukaryotes and is primarily involved in N6‐threonylcarbamoyl adenosine (t6A) modification...

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Bibliographic Details
Main Authors: Pengju Wu, Qi Gan, Xuemei Zhang, Yunfeng Yang, Yuanxi Xiao, Qunxin She, Jinfeng Ni, Qihong Huang, Yulong Shen
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:mLife
Subjects:
archaea
DNA homologous recombination repair
Gon7
KEOPS
t6A modification
Online Access:https://doi.org/10.1002/mlf2.12051

Internet

https://doi.org/10.1002/mlf2.12051

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