Understanding the benefit of metformin use in cancer treatment

<p>Abstract</p> <p>Biguanides have been developed for the treatment of hyperglycemia and type 2 diabetes. Recently, metformin, the most widely prescribed biguanide, has emerged as a potential anticancer agent. Epidemiological, preclinical and clinical evidence supports the use of m...

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Bibliographic Details
Main Authors: Goodwin Pamela J, Dowling Ryan JO, Stambolic Vuk
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/9/33