Crossing of the Cystic Barriers of <i>Toxoplasma gondii</i> by the Fluorescent Coumarin Tetra-Cyclopeptide

Crossing of the Cystic Barriers of <i>Toxoplasma gondii</i> by the Fluorescent Coumarin Tetra-Cyclopeptide

FR235222 is a natural tetra-cyclopeptide with a strong inhibition effect on histone deacetylases, effective on mammalian cells as well as on intracellular apicomplexan parasites, such as <i>Toxoplasma gondii,</i> in the tachyzoite and bradyzoite stages. This molecule is characterized by...

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Bibliographic Details
Main Authors: Céline Dard, Baptiste Leforestier, Flaviane Francisco Hilário, Mohamed Dit Mady Traoré, Marie-Ange Lespinasse, Basile Pérès, Marie-Carmen Molina, Rossimiriam Pereira de Freitas, Anne Milet, Danièle Maubon, Yung-Sing Wong
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
cyclopeptides
histone deacetylase
<i>Toxoplasma gondii</i>
bradyzoite
cell-permeable agent
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/26/24/7506

Internet

https://www.mdpi.com/1420-3049/26/24/7506

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