Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults

Summary: Background: The hard endpoint of death is one of the most significant outcomes in both clinical practice and research settings. Our goal was to discover direct causes of longevity from medically accessible data. Methods: Using a framework that combines local causal discovery algorithms wit...

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Bibliographic Details
Main Authors: Virginia Byers Kraus, Sisi Ma, Roshan Tourani, Gerda G. Fillenbaum, Bruce M. Burchett, Daniel C. Parker, William E. Kraus, Margery A. Connelly, James D. Otvos, Harvey Jay Cohen, Melissa C. Orenduff, Carl F. Pieper, Xin Zhang, Constantin F. Aliferis
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004741