Unveiling New Druggable Pockets in Influenza Non-Structural Protein 1: NS1–Host Interactions as Antiviral Targets for Flu

Unveiling New Druggable Pockets in Influenza Non-Structural Protein 1: NS1–Host Interactions as Antiviral Targets for Flu

Influenza viruses are responsible for significant morbidity and mortality worldwide in winter seasonal outbreaks and in flu pandemics. Influenza viruses have a high rate of evolution, requiring annual vaccine updates and severely diminishing the effectiveness of the available antivirals. Identifying...

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Bibliographic Details
Main Authors: Andreia E. S. Cunha, Rui J. S. Loureiro, Carlos J. V. Simões, Rui M. M. Brito
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
influenza
NS1
effector domain
molecular dynamics
druggability
protein–protein interactions
Online Access:https://www.mdpi.com/1422-0067/24/3/2977

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https://www.mdpi.com/1422-0067/24/3/2977

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