Sex-specific transcriptome differences in a middle-aged frailty cohort

Sex-specific transcriptome differences in a middle-aged frailty cohort

Abstract Background Frailty is a clinical syndrome described as reduced physiological reserve and increased vulnerability. Typically examined in older adults, recent work shows frailty occurs in middle-aged individuals and is associated with increased mortality. Previous investigation of global tran...

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Bibliographic Details
Main Authors: Natasha L. Pacheco, Nicole Noren Hooten, Yongqing Zhang, Calais S. Prince, Nicolle A. Mode, Ngozi Ezike, Kevin G. Becker, Alan B. Zonderman, Michele K. Evans
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Geriatrics
Subjects:
Midlife
Gene expression
Inflammation
Musculoskeletal
Aging
Online Access:https://doi.org/10.1186/s12877-022-03326-7

Internet

https://doi.org/10.1186/s12877-022-03326-7

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