Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis.

BACKGROUND & AIMS: The circadian clock drives daily rhythms in behavior and physiology. A recent study suggests that intestinal permeability is also under control of the circadian clock. However, the precise mechanisms remain largely unknown. Because intestinal permeability depends on tight junc...

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Bibliographic Details
Main Authors: Oh-oka Kyoko, Hiroshi Kono, Kayoko Ishimaru, Kunio Miyake, Takeo Kubota, Hideoki Ogawa, Ko Okumura, Shigenobu Shibata, Atsuhito Nakao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4028230?pdf=render