Impaired Kallikrein-Kinin System in COVID-19 Patients' Severity

Impaired Kallikrein-Kinin System in COVID-19 Patients' Severity

COVID-19 has emerged as a devastating disease in the last 2 years. Many authors appointed to the importance of kallikrein-kinin system (KKS) in COVID-19 pathophysiology as it is involved in inflammation, vascular homeostasis, and coagulation. We aim to study the bradykinin cascade and its involvemen...

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Bibliographic Details
Main Authors: Enrique Alfaro, Elena Díaz-García, Sara García-Tovar, Ester Zamarrón, Alberto Mangas, Raúl Galera, Kapil Nanwani-Nanwani, Rebeca Pérez-de-Diego, Eduardo López-Collazo, Francisco García-Río, Carolina Cubillos-Zapata
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
bradykinin (BK)
COVID-19
inflammation
thromboinflammation
NLRP3 inflammasome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.909342/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.909342/full

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