Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects

Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects

Controlled shortening of the poly(A) tail of mRNAs is the first step in eukaryotic mRNA decay and can also be used for translational inactivation of mRNAs. The CCR4-NOT complex is the most important among a small number of deadenylases, enzymes catalyzing poly(A) tail shortening. Rates of poly(A) sh...

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Bibliographic Details
Main Authors: Claudia eTemme, Martine eSimonelig, Elmar eWahle
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Genetics
Subjects:
development
translational control
mRNA decay
deadenylation
poly(A) tail
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00143/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00143/full

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