Role of thioredoxin-interacting protein in mediating endothelial dysfunction in hypertension

Excessive oxidative stress is a major causative factor of endothelial dysfunction in hypertension. As an endogenous pro-oxidant, thioredoxin-interacting protein (TXNIP) contributes to oxidative damage in various tissues. The present study aimed to investigate the role of TXNIP in mediating endotheli...

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Bibliographic Details
Main Authors: Ruiyu Wang, Yongzheng Guo, Lingjiao Li, Minghao Luo, Linqian Peng, Dingyi Lv, Zhe Cheng, Qian Xue, Liang Wang, Jing Huang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-05-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220301136