Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities.

Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities.

Adiponectin is an adipokine possessing beneficial effects on obesity-related medical complications. A negative association of adiponectin levels with breast cancer development has been demonstrated. However, the precise role of adiponectin deficiency in mammary carcinogenesis remains elusive.In the...

Full description

Bibliographic Details
Main Authors:	Janice B B Lam, Kim H M Chow, Aimin Xu, Karen S L Lam, Jing Liu, Nai-Sum Wong, Randall T Moon, Peter R Shepherd, Garth J S Cooper, Yu Wang
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2656613?pdf=render

Similar Items

Correction: Adiponectin Haploinsufficiency Promotes Mammary Tumor Development in MMTV-PyVT Mice by Modulation of Phosphatase and Tensin Homolog Activities
Published: (2009-01-01)

Characterization of Mammary Tumors Arising from MMTV-PyVT Transgenic Mice
by: Chien-Liang Liu, et al.
Published: (2023-05-01)

Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
by: Sharda P. Singh, et al.
Published: (2021-07-01)

Proteomic analysis of IgM antigens from mammary tissue under pre- and post-cancer conditions using the MMTV-PyVT mouse model
by: Ricardo Hernández Ávila, et al.
Published: (2022-10-01)

PyVT: A toolkit for preprocessing and analysis of vessel spatio-temporal trajectories
by: Ye Li, et al.
Published: (2023-02-01)

Collagen induced arthritis increases secondary metastasis in MMTV-PyV MT mouse model of mammary cancer
by: Gruber Helen E, et al.
Published: (2011-08-01)

Investigating the Role of Heparanase in Breast Cancer Development Utilising the MMTV-PyMT Murine Model of Mammary Carcinoma
by: Krishnath M. Jayatilleke, et al.
Published: (2023-06-01)

Phosphatase and tensin analog expression in arterial atherosclerotic lesions
by: Elancheran Muthalagan, et al.
Published: (2014-01-01)

Cholesteryl Ester Promotes Mammary Tumor Growth in MMTV-PyMT Mice and Activates Akt-mTOR Pathway in Tumor Cells
by: Lengyun Wei, et al.
Published: (2021-06-01)

High-Fat, High-Calorie Diet Enhances Mammary Carcinogenesis and Local Inflammation in MMTV-PyMT Mouse Model of Breast Cancer
by: Sarah Cowen, et al.
Published: (2015-06-01)

Mouse Mammary Tumor Virus (MMTV) and MMTV-like Viruses: An In-depth Look at a Controversial Issue
by: Francesca Parisi, et al.
Published: (2022-05-01)

MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model
by: Mei Qi Kwa, et al.
Published: (2021-04-01)

A PDE Model of Breast Tumor Progression in MMTV-PyMT Mice
by: Navid Mohammad Mirzaei, et al.
Published: (2022-05-01)

Comparison of Expression Profiles of Metastatic versus Primary Mammary Tumors in MMTV-Wnt-1 and MMTV-Neu Transgenic Mice
by: Shixia Huang, et al.
Published: (2008-02-01)

Transmembrane Phosphatase with TEnsin Homologue (TPTE) Expression in Epithelial Ovarian Cancer
by: CA Adepiti, et al.
Published: (2022-06-01)

Mammary Tumorigenesis and Metabolome in Male Adipose Specific Monocyte Chemotactic Protein-1 Deficient MMTV-PyMT Mice Fed a High-Fat Diet
by: Lin Yan, et al.
Published: (2021-09-01)

Chronic Stress Exposure Suppresses Mammary Tumor Growth and Reduces Circulating Exosome TGF-β Content via β-Adrenergic Receptor Signaling in MMTV-PyMT Mice
by: Ryan P Dawes, et al.
Published: (2020-06-01)

Immunohistochemical expression of phosphatase and tensin homolog in histologic gradings of oral squamous cell carcinoma
by: Shiny S.R. Jasphin, et al.
Published: (2016-01-01)

The complexity of phosphatase and tensin homolog hamartoma tumor syndrome: A case report
by: Kakha Bregvadze, et al.
Published: (2024-04-01)

Pathological Features and Molecular Phenotype of MMTV Like-Positive Feline Mammary Carcinomas
by: Francesca Parisi, et al.
Published: (2021-09-01)

Mouse mammary tumour virus (MMTV) and human breast cancer with neuroendocrine differentiation
by: Lawson JS, et al.
Published: (2017-05-01)

Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model.
by: Christian Franci, et al.
Published: (2013-01-01)

S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis
by: Alamelu G. Bharadwaj, et al.
Published: (2020-12-01)

Phosphatase and Tensin Homologue Genetic Polymorphisms and their Interactions with Viral Mutations on the Risk of Hepatocellular Carcinoma
by: Yan Du, et al.
Published: (2015-01-01)

Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors
by: Xu WT, et al.
Published: (2014-10-01)

Silymarin induces insulin resistance through an increase of phosphatase and tensin homolog in Wistar rats.
by: Kai-Chun Cheng, et al.
Published: (2014-01-01)

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer.
by: Elisabeth P Cramer, et al.
Published: (2012-01-01)

A Milk-Fat Based Diet Increases Metastasis in the MMTV-PyMT Mouse Model of Breast Cancer
by: Fabiola N. Velazquez, et al.
Published: (2021-07-01)

Treatment response assessment with (R)-[11CPAQ PET in the MMTV-PyMT mouse model of breast cancer
by: T. Tegnebratt, et al.
Published: (2018-04-01)

Correction to: mouse mammary tumour virus (MMTV) and human breast cancer with neuroendocrine differentiation
by: J. S. Lawson, et al.
Published: (2017-10-01)

Global Down-regulation of Gene Expression Induced by Mouse Mammary Tumor Virus (MMTV) in Normal Mammary Epithelial Cells
by: Waqar Ahmad, et al.
Published: (2023-05-01)

Deletion of <i>Col15a1</i> Modulates the Tumour Extracellular Matrix and Leads to Increased Tumour Growth in the <i>MMTV-PyMT</i> Mouse Mammary Carcinoma Model
by: Guillermo Martínez-Nieto, et al.
Published: (2021-09-01)

Loss of phosphatase activity in PTEN (phosphatase and tensin homolog deleted on chromosome ten) results in endometrial carcinoma in humans: An in-silico study
by: Sunil Kanti Mondal, et al.
Published: (2020-01-01)

Expression pattern of phosphatase and tensin homolog and epidermal growth factor receptor in patients with brain tumor
by: Ananthan Raghotham, et al.
Published: (2023-01-01)

Neuronal deletion of phosphatase and tensin homolog in mice results in spatial dysregulation of adult hippocampal neurogenesis
by: Sarah E. Latchney, et al.
Published: (2023-12-01)

Relationship between phosphatase and tensin homolog (PTEN) expression in high grade glioma and histopathologic findings
by: Nasim Hayati, et al.
Published: (2021-12-01)

Phosphatase and Tensin Homolog in Non-neoplastic Digestive Disease: More Than Just Tumor Suppressor
by: Tianyu He, et al.
Published: (2021-06-01)

Phosphatase and Tensin Homolog Mutation in Immune Cell Infiltration and Clinicopathological Features of Low-Grade Gliomas
by: Peng Feng, et al.
Published: (2020-12-01)

Mouse Mammary Tumour Virus (MMTV) in Human Breast Cancer—The Value of Bradford Hill Criteria
by: James S. Lawson, et al.
Published: (2022-03-01)

The Involvement of Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN) in the Regulation of Inflammation Following Coronary Microembolization
by: Jiangyou Wang, et al.
Published: (2014-06-01)