Genotype-guided new approach for dose optimisation of hydroxychloroquine administration in Chinese patients with SLE

Objectives The study aims to investigate the impact of gene polymorphisms on blood hydroxychloroquine (HCQ) concentrations in patients with SLE and provide guidelines for individualised care.Methods 489 Chinese patients with SLE taking HCQ for more than 3 months were collected in this study. The blo...

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Bibliographic Details
Main Authors: Lingyun Sun, Wei Shen, Ziyi Jin, Dandan Wang, Yizhun Zhu, Linyu Geng, Han Xie, Xin Wen, Yuchun Wang, Xuan Huang, Qing Shu, Weihong Ge
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/10/2/e000997.full