A framework for multiplex imaging optimization and reproducible analysis

An approach for tissue image analysis applicable to highly multiplexed immunofluorescence imaging of the spatial distribution of multiple protein biomarkers is proposed, here applied to the analysis of multiplex IF using the multiplex imaging platform, CyCIF.

Bibliographic Details
Main Authors: Jennifer Eng, Elmar Bucher, Zhi Hu, Ting Zheng, Summer L. Gibbs, Koei Chin, Joe W. Gray
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03368-y