Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases.

BACKGROUND:There is an urgent need for the discovery and development of new drugs against Mycobacterium tuberculosis, the causative agent of tuberculosis, especially due to the recent emergence of multi-drug and extensively-drug resistant strains. Herein, we have examined the susceptibility of mycob...

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Bibliographic Details
Main Authors: Alistair K Brown, Rebecca C Taylor, Apoorva Bhatt, Klaus Fütterer, Gurdyal S Besra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2707616?pdf=render