Dutch population structure across space, time and GWAS design

Genetic variation in modern humans can reveal information about a population’s history and migration patterns. Here, the authors describe the ancestry and geospatial genetic structure of the Netherlands, and demonstrate the utility of haplotype-based covariates in genome-wide association studies.

Bibliographic Details
Main Authors: Ross P. Byrne, Wouter van Rheenen, Project MinE ALS GWAS Consortium, Leonard H. van den Berg, Jan H. Veldink, Russell L. McLaughlin
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18418-4