Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

Epigenetic perturbations may be an important factor in diseases where both genes and environment play a role. Here, Ventham and colleagues show that DNA methylation changes in inflammatory bowel disease are related to the underlying genotype, and are associated with cell-specific changes to gene exp...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: N. T. Ventham, N. A. Kennedy, A. T. Adams, R. Kalla, S. Heath, K. R. O'Leary, H. Drummond, IBD BIOM consortium, IBD CHARACTER consortium, D. C. Wilson, I. G. Gut, E. R. Nimmo, J. Satsangi
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2016-11-01
श्रृंखला:Nature Communications
ऑनलाइन पहुंच:https://doi.org/10.1038/ncomms13507

इंटरनेट

https://doi.org/10.1038/ncomms13507

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