A cascade targeting strategy based on modified bacterial vesicles for enhancing cancer immunotherapy

Abstract Background As an efficient tumor immunotherapy, PD-1 antibody has been gradually used in clinical tumor treatment, but the low response rate and excessive immune response limit its extensive application. Results Herein, a therapeutic regime for the reinvigoration and activation of the tumor...

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Bibliographic Details
Main Authors: Yuewen Zhai, Yuying Ma, Bo Pang, Jinnan Zhang, Ying Li, Yalan Rui, Tian Xu, Yu Zhao, Zhiyu Qian, Yueqing Gu, Siwen Li
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-021-01193-9